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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSNK1A1
All Species:
45.76
Human Site:
T169
Identified Species:
71.9
UniProt:
P48729
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48729
NP_001020276.1
337
38915
T169
K
K
Y
R
D
N
R
T
R
Q
H
I
P
Y
R
Chimpanzee
Pan troglodytes
XP_001163892
341
39357
T173
K
K
Y
R
D
N
R
T
R
Q
H
I
P
Y
R
Rhesus Macaque
Macaca mulatta
XP_001106705
339
39093
T171
K
K
Y
R
D
N
R
T
R
Q
H
I
P
Y
R
Dog
Lupus familis
XP_867638
336
38749
T169
K
K
Y
R
D
N
R
T
R
Q
H
I
P
Y
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMK2
416
47304
T161
K
K
Y
R
D
A
R
T
H
Q
H
I
P
Y
R
Rat
Rattus norvegicus
P97633
325
37477
F154
G
R
H
C
N
K
L
F
L
I
D
F
G
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P67962
337
38882
T169
K
K
Y
R
D
N
R
T
R
Q
H
I
P
Y
R
Frog
Xenopus laevis
Q5BP74
415
47421
T161
K
K
Y
R
D
A
R
T
H
Q
H
I
P
Y
R
Zebra Danio
Brachydanio rerio
Q7T2E3
403
46225
T161
K
K
Y
R
D
A
R
T
H
Q
H
I
P
Y
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54367
337
39516
K165
L
I
D
F
G
L
A
K
K
F
R
D
P
H
T
Honey Bee
Apis mellifera
XP_393612
350
40282
T173
K
K
Y
R
D
S
R
T
R
M
H
I
M
Y
R
Nematode Worm
Caenorhab. elegans
P42168
341
39018
T168
K
K
Y
R
D
S
R
T
R
T
H
I
P
Y
R
Sea Urchin
Strong. purpuratus
XP_786391
348
40003
F168
G
R
H
C
N
Q
L
F
L
I
D
F
G
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
T161
K
K
Y
R
D
S
T
T
H
Q
H
I
P
Y
R
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
T161
K
K
Y
R
D
F
N
T
H
R
H
I
P
Y
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97.6
99.6
N.A.
57.2
96.1
N.A.
N.A.
99.6
57.5
59.5
N.A.
74.1
80.8
81.2
78.7
Protein Similarity:
100
98.8
98.2
99.6
N.A.
67.7
96.1
N.A.
N.A.
100
67.9
70.2
N.A.
82.7
86.8
86.8
87.3
P-Site Identity:
100
100
100
100
N.A.
86.6
0
N.A.
N.A.
100
86.6
86.6
N.A.
6.6
80
86.6
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
20
N.A.
N.A.
100
86.6
86.6
N.A.
20
86.6
93.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
50.2
41.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.1
54.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
80
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
20
7
0
0
0
0
0
0
0
14
% A
% Cys:
0
0
0
14
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
80
0
0
0
0
0
14
7
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
7
0
7
0
14
0
7
0
14
0
0
0
% F
% Gly:
14
0
0
0
7
0
0
0
0
0
0
0
14
0
0
% G
% His:
0
0
14
0
0
0
0
0
34
0
80
0
0
7
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
14
0
80
0
0
0
% I
% Lys:
80
80
0
0
0
7
0
7
7
0
0
0
0
0
0
% K
% Leu:
7
0
0
0
0
7
14
0
14
0
0
0
0
14
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% M
% Asn:
0
0
0
0
14
34
7
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
80
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
60
0
0
0
0
0
% Q
% Arg:
0
14
0
80
0
0
67
0
47
7
7
0
0
0
80
% R
% Ser:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
7
80
0
7
0
0
0
0
7
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
80
0
0
0
0
0
0
0
0
0
0
80
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _